What car features matter most for road trip comfort?

The features that make the biggest difference on a long road trip are: adaptive cruise control with lane centering (reduces driver fatigue dramatically on highway stretches), front seat comfort and lumbar support (how the seat feels after three hours is very different from how it feels in a showroom), cabin noise insulation at highway speeds, a large fuel tank or long electric range to minimize stops, wireless Apple CarPlay or Android Auto, and rear seat comfort if you are traveling with passengers. Heated and ventilated seats are also underrated on long drives in both cold and hot conditions.